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Comment
. 2013 Apr 4;12(4):383-4.
doi: 10.1016/j.stem.2013.03.011.

Short telomeres flirt with stem cell commitment

Rich Allsopp  1
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Short telomeres flirt with stem cell commitment

Rich Allsopp. Cell Stem Cell. .
Free article

Abstract

High expression of telomerase in embryonic stem cells (ESCs) is important for their maintenance, but whether telomere length affects lineage commitment is unknown. In this issue of Cell stem cell, Pucci et al. (2013) reveal that ESCs with short telomeres exhibit unstable differentiation by inducing altered DNA methylation.

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