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. 2013 Apr 2;17(4):469-70.
doi: 10.1016/j.cmet.2013.03.011.

Insulin and ventral tegmental dopamine: what's impaired and what's intact?

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Insulin and ventral tegmental dopamine: what's impaired and what's intact?

John D Salamone et al. Cell Metab. .
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Abstract

Manipulations affecting mesolimbic dopamine transmission exert specific effects on normal and pathological aspects of motivation, altering some functions while sparing others. Labouèbe et al. (2013) show that insulin induced long-term depression in ventral tegmental neurons, which was associated with reduced responsiveness to food-related stimuli but spared aspects of food-seeking behavior.

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