Review
doi: 10.1055/s-0033-1338110.
Epub 2013 Apr 5.
Molecular virology of hepatitis E virus
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- PMID: 23564385
- DOI: 10.1055/s-0033-1338110
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Review
Molecular virology of hepatitis E virus
Semin Liver Dis.
2013 Feb.
Abstract
Hepatitis E virus (HEV) is the causative agent of hepatitis E. It is a nonenveloped virus with a ∼7.2 kilobases positive-stranded RNA genome. The molecular virology of HEV is getting better understood with the development of replicons and in vitro infection systems, and the discovery of related viruses that infect animal species other than humans. This review focuses on the virology of HEV and updates the current knowledge on the HEV genome and its constituent proteins--ORF1, ORF2, and ORF3, and the viral life cycle.
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
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