Assessing bone health in children and adolescents
- PMID: 23565379
- PMCID: PMC3603027
- DOI: 10.4103/2230-8210.104040
Assessing bone health in children and adolescents
Abstract
During normal childhood and adolescence, the skeleton undergoes tremendous change. Utilizing the processes of modeling and remodeling, the skeleton acquires its adult configuration and ultimately achieves peak bone mass. Optimization of peak bone mass requires the proper interaction of environmental, dietary, hormonal, and genetic influences. A variety of acute and chronic conditions, as well as genetic polymorphisms, are associated with reduced bone density, which can lead to an increased risk of fracture both in childhood and later during adulthood. Bone densitometry has an established role in the evaluation of adults with bone disorders, and the development of suitable reference ranges for children now permits the application of this technology to younger individuals. We present a brief overview of the factors that determine bone density and the emerging role of bone densitometry in the assessment of bone mass in growing children and adolescents.
Keywords: Bone health; adolescents; children.
Conflict of interest statement
References
-
- Rauch F. Bone accrual in children: Adding substance to surfaces. Pediatrics. 2007;119(Suppl 2):S137–40. - PubMed
-
- Bachrach LK. Acquisition of optimal bone mass in childhood and adolescence. Trends Endocrinol Metab. 2001;12:22–8. - PubMed
-
- Tanner JM, Whitehouse RH, Marubini E, Resele LF. The adolescent growth spurt of boys and girls of the Harpenden growth study. Ann Hum Biol. 1976;3:109–26. - PubMed
-
- Bradney M, Karlsson MK, Duan Y, Stuckey S, Bass S, Seeman E. Heterogeneity in the growth of the axial and appendicular skeleton in boys: Implications for the pathogenesis of bone fragility in men. J Bone Miner Res. 2000;15:1871–8. - PubMed
Grants and funding
LinkOut - more resources
Full Text Sources