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Case Reports
. 1990 Jun;299(6):366-71.
doi: 10.1097/00000441-199006000-00002.

Hemolytic-uremic syndrome following "crack" cocaine inhalation

J A Tumlin  1 , J M Sands, A Someren
Affiliations
Case Reports

Hemolytic-uremic syndrome following "crack" cocaine inhalation

J A Tumlin et al. Am J Med Sci. 1990 Jun.

Abstract

The authors present a patient who experienced cocaine-related thrombotic microangiopathy and patchy renal cortical necrosis, associated with the clinical syndrome of microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure, characteristics of the Hemolytic-Uremic syndrome. The proposed pathogenetic mechanisms include: (1) cocaine-induced vasoconstriction and endothelial damage and (2) procoagulant effects of cocaine.

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