Dengue fever treatment with Carica papaya leaves extracts
- PMID: 23569787
- PMCID: PMC3614241
- DOI: 10.1016/S2221-1691(11)60055-5
Dengue fever treatment with Carica papaya leaves extracts
Abstract
The main objective of the current study is to investigate the potential of Carica papaya leaves extracts against Dengue fever in 45 year old patient bitten by carrier mosquitoes. For the treatment of Dengue fever the extract was prepared in water. 25 mL of aqueous extract of C. papaya leaves was administered to patient infected with Dengue fever twice daily i.e. morning and evening for five consecutive days. Before the extract administration the blood samples from patient were analyzed. Platelets count (PLT), White Blood Cells (WBC) and Neutrophils (NEUT) decreased from 176×10(3)/µL, 8.10×10(3)/µL, 84.0% to 55×10(3)/µL, 3.7×10(3)/µL and 46.0%. Subsequently, the blood samples were rechecked after the administration of leaves extract. It was observed that the PLT count increased from 55×10(3)/µL to 168×10(3)/µL, WBC from 3.7×10(3)/µL to 7.7×10(3)/µL and NEUT from 46.0% to 78.3%. From the patient feelings and blood reports it showed that Carica papaya leaves aqueous extract exhibited potential activity against Dengue fever. Furthermore, the different parts of this valuable specie can be further used as a strong natural candidate against viral diseases.
Keywords: Carica papaya; Dengue fever; Leaves extracts; Platelets; Potential activity.
Conflict of interest statement
Figures
References
-
- Murthy JM, Rani PU. Biological activity of certain botanical extracts as larvicides against the yellow fever mosquito, Aedes aegypti L. J Biopest. 2009;2:72–76.
-
- Akram W, Khan HAA, Hafeez F, Bilal H, Kim YK, Lee JJ. Potential of citrus seed extracts against Dengue fever mosquito, Aedes albopic Tus (Skuse) (Culicidaea) Pak J Bot. 2010;42:3343–3348.
-
- Maheswaran R, Satish S, Ignacimathu S. Larvicidal activity of Leucas asper (Willd) against the larvae of Culex quinquefasciatus Say. and Aedes aegypti L. Inter J Integrative Biol. 2008;2:214–217.
-
- Moreno-Sanchez R, Hayden M, Janes C. A web-based multimedia spatial information system to document Aedes aegypti breeding sites and dengue fever risk along the US-Mexico border. Health & Place. 2006;12:715–727. - PubMed
-
- Morens, Fauci, Brody JE. Mosquito thrives; so does dengue fever. Geneva: WHO; 2008.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
