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. 2011 Oct;1(5):395-400.
doi: 10.1016/S2221-1691(11)60087-7.

Pedalium murex Linn (Pedaliaceae) fruits: a comparative antioxidant activity of its different fractions

D K Patel  1 , R Kumar, S K Prasad, S Hemalatha
Affiliations

Pedalium murex Linn (Pedaliaceae) fruits: a comparative antioxidant activity of its different fractions

D K Patel et al. Asian Pac J Trop Biomed. 2011 Oct.

Abstract

Objective: To examine the antioxidant activity and total phenolic content of different solvent fractions of Pedalium murex (P. murex) Linn fruits (Family: Pedaliaceae) as well as the correlation between the total antioxidant capacity and total phenolic content.

Methods: In the present study, the antioxidant activities of P. murex were evaluated using six in-vitro assays, namely total antioxidant assay, DPPH assay, reducing power, nitric oxide scavenging, hydrogen peroxide scavenging and deoxyribose scavenging assays, and total phenol contents were also investigated.

Results: The ethyl acetate (EA) fraction was found to have high levels of phenolic content (298.72±2.09 mg GAE/g). The EA fraction exhibit higher total antioxidant capacity, higher percentage of DPPH radical scavenging activity (135.11±2.95µg/mL), nitric oxide (200.57±4.51µg/mL), hydrogen peroxide (217.91±6.12 µg/mL), deoxyribose (250.01±4.68µg/mL) and higher reducing power. Correlation coefficient (r(2) =0.914) was found to be significant between total phenolic content and total antioxidant activity.

Conclusions: In general, the results indicate that the EA fractions are rich in phenolic antioxidants with potent free radical scavenging activity implying their importance to human health.

Keywords: Antioxidant activity; Different solvent fraction; In vitro assay; Pedalium murex; Scavenging activity; Total phenolics.

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Conflict of interest statement

Conflict of interest statement: We declare that we have no conflict of interest.

Figures

Figure 1.
Figure 1.. Schematic diagram of fractionation of P. murex extract.
Figure 2.
Figure 2.. Total antioxidant capacity and assay of reducing power of different fraction of P. murex.
STD: Rutin; PET: petroleum ether; CHLO: chloroform; EA: ethyl acetate; AQ: aqueous.
Figure 3.
Figure 3.. Correlations between the total antioxidant capacity and total phenolic content of different fraction of P. murex.
See this image and copyright information in PMC

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