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. 2013:2013:589620.
doi: 10.1155/2013/589620. Epub 2013 Mar 14.

Corneal Transplant Infection due to Alternaria alternata: A Case Report

Vasileios Konidaris  1 , Andreana Mersinoglou, Timoleon-Achilleas Vyzantiadis, Domniki Papadopoulou, Kostas G Boboridis, Panagiotis Ekonomidis
Affiliations

Corneal Transplant Infection due to Alternaria alternata: A Case Report

Vasileios Konidaris et al. Case Rep Ophthalmol Med. 2013.

Abstract

Purpose. To report a case of Alternaria alternata keratitis in a patient with a corneal transplant in her right eye due to bullous pseudophakic keratopathy. Methods. A 66-year-old female underwent a full-thickness keratoplasty in her right eye due to bullous pseudophakic keratopathy. Three weeks after keratoplasty, epithelial edema and a stromal opacity with an infiltrate and development of peripheral corneal opacities appeared. The diagnosis of Alternaria alternata keratitis was made. Results. The patient underwent a second keratoplasty, due to the corneal melting as a result of the fungal infection. She was also given combined antifungal treatment locally and systematically. Conclusion. Corneal transplantation alone would not have been sufficient to keep the fungus in the anterior portion of the eye. Combined antifungal treatment, locally and systematically, was important in attempting to prevent the further spread of the fungus to the interior of the eye. To our knowledge, the case presented here is only the second one in the literature concerning a keratomycosis due to Alternaria alternata corneal transplant infection.

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Figures

Figure 1
Figure 1
Epithelial edema and stromal opacity with an infiltrate and development of peripheral opacities three weeks after keratoplasty in the right eye.
Figure 2
Figure 2
Tape mount with lactophenol-cotton blue. Chains of conidia with multiple septa (×400).
Figure 3
Figure 3
Central ulceration and abscess with indistinct margins, involving the central corneal zone.
See this image and copyright information in PMC

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