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. 2012:32:35-9.

Liposclerosing myxofibrous tumor (LSMFT), a study of 33 patients: should it be a distinct entity?

Jonathan Dattilo  1 , Edward F McCarthy
Affiliations

Liposclerosing myxofibrous tumor (LSMFT), a study of 33 patients: should it be a distinct entity?

Jonathan Dattilo et al. Iowa Orthop J. 2012.

Abstract

Liposclerosing myxoid fibrous tumor (LSMFT) is a recently described bone lesion site specific to the proximal femur. We have studied the radiographs and clinical features of 33 patients with this disorder. Histologic material was available for study in 18 of these patients. Histologic study revealed that 12 of these 18 had an underlying fibrous dysplasia and these had an underlying intraosseous lipoma. Because of this histologic evidence as well as the radiographic spectrum of the other lesions, we conclude that LSMFT is not a specific lesion and use of the term should be discontinued.

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Figures

Figure 1
Figure 1. AP radiograph showing an LSMFT in the proximal femur. The lesion is well demarcated with a broad sclerotic rim. It shows intralesional densities.
Figure 2
Figure 2. LSMFT showing a faint ground-glass pattern which is suggestive of fibrous dysplasia.
Figure 3
Figure 3. A well-defined lytic lesion in the femur with a central radiodensity. This pattern is highly suggestive an interosseous lipoma.
Figure 4
Figure 4. Photomicrograph showing areas of fibrosis and myxoid change. This is a pattern common to all cases of LSMFT.
Figure 5
Figure 5. Photomicrograph showing a fibroosseous lesion which is diagnostic of fibrous dysplasia. This finding was present in twelve cases.
Figure 6
Figure 6. Photomicrograph showing adipose tissue with a central amorphous calcification. This pattern is common in degenerated areas of interosseous lipoma. This finding was present in three cases.
See this image and copyright information in PMC

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