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Case Reports
. 2013 Dec;38(12):e465-6.
doi: 10.1097/RLU.0b013e3182867581.

Distinctive PET/CT features of splenic SANT

Yu-Min Feng  1 , Ying Chieh Huang, Chi-Wen Tu, Wen-Shih Kao, Dom-Gene Tu
Affiliations
Case Reports

Distinctive PET/CT features of splenic SANT

Yu-Min Feng et al. Clin Nucl Med. 2013 Dec.

Abstract

A 44-year-old woman suffered from epigastralgia for 1 month. An abdominal sonography revealed a space-occupying lesion, about 6 cm, in the spleen. Contrast-enhanced CT revealed enhanced splenic lesions. The PET/CT showed FDG-avid multiple splenic nodules with a "prunes on bread" appearance in the maximum-intensity-projection image (MIP image). In sectional PET/CT images, a central cold area with peripheral increased FDG uptake in the splenic nodule is visible. Because splenic malignancy was suspected, laparoscopic splenectomy was performed. Histology revealed multiple nodules with angiomatoid appearance, CD31(+), CD34(+) and HHV-8(-) in the vascular space, typical for the rare sclerosing angiomatoid nodular transformation (SANT).

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