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Case Reports
. 2013 Aug;68(8):1926-8.
doi: 10.1093/jac/dkt117. Epub 2013 Apr 11.

Evolution of high-level daptomycin resistance in Enterococcus faecium during daptomycin therapy is associated with limited mutations in the bacterial genome

Theodoros Kelesidis, Ryan Tewhey, Romney M Humphries
Case Reports

Evolution of high-level daptomycin resistance in Enterococcus faecium during daptomycin therapy is associated with limited mutations in the bacterial genome

Theodoros Kelesidis et al. J Antimicrob Chemother. 2013 Aug.
No abstract available

Keywords: cardiolipin synthetase; hypercalcaemia; whole-genome sequencing.

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References

    1. Kelesidis T, Humphries R, Uslan DZ, et al. Daptomycin nonsusceptible enterococci: an emerging challenge for clinicians. Clin Infect Dis. 2011;52:228–34. - PMC - PubMed
    1. Kelesidis T, Humphries R, Uslan DZ, et al. De novo daptomycin-nonsusceptible enterococcal infections. Emerg Infect Dis. 2012;18:674–6. - PMC - PubMed
    1. Kelesidis T, Chow AL, Humphries R, et al. Case-control study comparing de novo and daptomycin-exposed daptomycin-nonsusceptible Enterococcus infections. Antimicrob Agents Chemother. 2012;56:2150–2. - PMC - PubMed
    1. Clinical and Laboratory Standards Institute. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically—Ninth Edition: Approved Standard M07-A9. Wayne, PA, USA: CLSI; 2012.
    1. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing: Twenty-second Informational Supplement: M100-S22. Wayne, PA, USA: CLSI; 2012.

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