Xpert MTB/RIF testing of stool samples for the diagnosis of pulmonary tuberculosis in children
- PMID: 23580738
- PMCID: PMC3703104
- DOI: 10.1093/cid/cit230
Xpert MTB/RIF testing of stool samples for the diagnosis of pulmonary tuberculosis in children
Erratum in
- Clin Infect Dis. 2014 Jul 1;59(1):145
Abstract
In a pilot accuracy study, stool Xpert testing from 115 children with suspected pulmonary tuberculosis (PTB) detected 8/17 (47%) culture-confirmed tuberculosis cases, including 4/5 (80%) HIV-infected and 4/12 (33%) HIV-uninfected children. Sputum Xpert detected 11/17 (65%) cases. Stool holds promise for PTB diagnosis in HIV-infected children.
Keywords: Xpert; children; diagnosis; stool; tuberculosis.
References
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- Bates M, O'Grady J, Maeurer M, et al. Assessment of the Xpert MTB/RIF assay for diagnosis of tuberculosis with gastric lavage aspirates in children in sub-Saharan Africa: a prospective descriptive study. Lancet Infect Dis. 2013;13:36–42. - PubMed
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- Donald PR, Schaaf HS, Gie RP, Beyers N, Sirgel FA, Venter A. Stool microscopy and culture to assist the diagnosis of pulmonary tuberculosis in childhood. J Trop Pediatr. 1996;42:311–2. - PubMed
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