Influence of seroreactivity to leptospira and reproductive failures in recipient mares of equine embryo transfer programmes

Abstract

The aim of this study was to demonstrate that seroreactivity against Leptospira is significantly associated to the reproductive efficiency of recipient mares of an embryo transfer (ET) programme. A serosurvey was conducted from August 2007 to March 2009 in five herds from Rio de Janeiro, Brazil, with high rates of reproductive failure, as early embryonic death (>12%), abortion (>12%) and perinatal death. Detailed information about the losses was obtained from practitioner. A total of 338 recipient mares were tested by microscopic agglutination test, and 226 (66.9%) were seroreactive, mainly against serovars Bratislava and Copenhageni. Seroreactivity could be associated to reproductive failure (p < 0.001), and it was demonstrated that a seroreactive mare is 1.8 times more likely (relative risk - RR) to present reproductive failure than a seronegative one, particularly in relation to early embryonic death (p < 0.0001; RR 8.4) but also to abortions (p < 0.0001; RR 3.5), and to perinatal death (p < 0.05; RR 7.3). Therefore, seroreactivity to Leptospira is associated to reproductive failure in all phases of pregnancy in recipient mares, impairing equine ET programmes.