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. 2013 Aug;197(2):182-7.
doi: 10.1016/j.tvjl.2013.02.021. Epub 2013 Apr 11.

A web resource on DNA tests for canine and feline hereditary diseases

Jeffrey Slutsky  1 , Karthik Raj, Scott Yuhnke, Jerold Bell, Neale Fretwell, Ake Hedhammar, Claire Wade, Urs Giger
Affiliations

A web resource on DNA tests for canine and feline hereditary diseases

Jeffrey Slutsky et al. Vet J. 2013 Aug.

Abstract

Following the first identification of a disease-causing mutation in dogs in 1989 and the more recent completion of canine and feline genome sequences, much progress has been made in the molecular characterization of hereditary diseases in dogs and cats. To increase access to information on diagnosing hereditary diseases in dogs and cats, a web application has been developed to collect, organize and display information on available DNA tests and other supporting information, including gene and chromosomal locations, mutations, primary research citations and disease descriptions. The DNA testing information can be accessed at the URL: http://research.vet.upenn.edu/WSAVA-LabSearch. There are currently 131 molecular genetic tests available for hereditary diseases in dogs and cats offered by 43 laboratories worldwide. This tool should provide clinicians, researchers, breeders and companion animal owners with a single comprehensive, up-to-date and readily searchable webpage for information on hereditary disease testing.

Keywords: Canine; Database; Feline; Genetics; Mutations.

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Conflict of interest statement

Conflict of interest statement

The authors from the University of Pennsylvania are associated with PennGen, one of the not-for-profit laboratories offering DNA tests, and the work was funded by the WSAVA through contributions from Waltham.

Figures

Fig. 1
Fig. 1
A sample disease test search for a coagulopathy in Beagles. (A) Searches can be done by disease/test, breed or laboratory. (B) Information regarding the selection is used to narrow down the results. (C) Information about the specific disease in this breed is displayed. (D) Information about the laboratories doing the specific test in this breed is displayed.
See this image and copyright information in PMC

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