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doi: 10.1016/j.neuron.2013.03.012.
Microtubule stability in the axon: new answers to an old mystery
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- PMID: 23583103
- DOI: 10.1016/j.neuron.2013.03.012
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Microtubule stability in the axon: new answers to an old mystery
Neuron.
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Abstract
It has been known for decades that a fraction of neuronal tubulin is insoluble in cold and also resistant to calcium as well as drugs that depolymerize microtubules. In this issue of Neuron, Song et al. (2013) suggest that this unusual stability results from the polyamination of tubulin by transglutaminase.
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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Transglutaminase and polyamination of tubulin: posttranslational modification for stabilizing axonal microtubules.Neuron. 2013 Apr 10;78(1):109-23. doi: 10.1016/j.neuron.2013.01.036. Neuron. 2013. PMID: 23583110 Free PMC article.
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