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Case Reports
. 2013 Apr;59(4):373-5.

Clinically important interaction between metoprolol and propafenone

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Case Reports

Clinically important interaction between metoprolol and propafenone

Jana Duricova et al. Can Fam Physician. 2013 Apr.
No abstract available

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References

    1. Kroemer HK, Fischer C, Meese CO, Eichelbaum M. Enantiomer/enantiomer interaction of (S)- and (R)-propafenone for cytochrome P450IID6-catalyzed 5-hydroxylation: in vitro evaluation of the mechanism. Mol Pharmacol. 1991;40(1):135–42. - PubMed
    1. Otton SV, Inaba T, Kalow W. Competitive inhibition of sparteine oxidation in human liver by beta-adrenoceptor antagonists and other cardiovascular drugs. Life Sci. 1984;34(1):73–80. - PubMed
    1. Frank D, Jaehde U, Fuhr U. Evaluation of probe drugs and pharmacokinetic metrics for CYP2D6 phenotyping. Eur J Clin Pharmacol. 2007;63(4):321–33. Epub 2007 Feb 2. - PubMed
    1. Abrahamsson B, Lücker P, Olofsson B, Regårdh CG, Sandberg A, Wieselgren I, et al. The relationship between metoprolol plasma concentration and beta 1-blockade in healthy subjects: a study on conventional metoprolol and metoprolol CR/ZOK formulations. J Clin Pharmacol. 1990;30(2 Suppl):S46–54. - PubMed
    1. Regårdh CG, Johnsson G. Clinical pharmacokinetics of metoprolol. Clin Pharmacokinet. 1980;5(6):557–69. - PubMed

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