Enduring mystery of the chromosome 9p21.3 locus

Affiliations

Comment

Kiran Musunuru. Circ Cardiovasc Genet. 2013 Apr.

. 2013 Apr;6(2):224-5.

doi: 10.1161/CIRCGENETICS.113.000132.

¹ Early Career Committee of the American Heart Association Functional Genomics and Translational Biology Council. kiranmusunuru@gmail.com

No abstract available

Comment on

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response.
Harismendy O, Notani D, Song X, Rahim NG, Tanasa B, Heintzman N, Ren B, Fu XD, Topol EJ, Rosenfeld MG, Frazer KA. Harismendy O, et al. Nature. 2011 Feb 10;470(7333):264-8. doi: 10.1038/nature09753. Nature. 2011. PMID: 21307941 Free PMC article.
Interferon-γ activates expression of p15 and p16 regardless of 9p21.3 coronary artery disease risk genotype.
Almontashiri NA, Fan M, Cheng BL, Chen HH, Roberts R, Stewart AF. Almontashiri NA, et al. J Am Coll Cardiol. 2013 Jan 15;61(2):143-7. doi: 10.1016/j.jacc.2012.08.1020. Epub 2012 Nov 28. J Am Coll Cardiol. 2013. PMID: 23199516