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. 2013;75(9):1223-5.
doi: 10.1292/jvms.12-0450. Epub 2013 Apr 18.

Efficient propagation of equine viruses in a newly established equine cell line, FHK-13.1 cells

Keisuke Oguma  1 , Maiko Ishida, Ken Maeda, Hiroshi Sentsui
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Free article

Efficient propagation of equine viruses in a newly established equine cell line, FHK-13.1 cells

Keisuke Oguma et al. J Vet Med Sci. 2013.
Free article

Abstract

Equine cells are required for isolation of viruses that infect the horse. However, only a few equine cell lines and cell cultures are available so far. Fetal horse kidney (FHK)-Tcl3.1 cell is a novel cell line established by introducing simian virus 40 (SV40) large T antigen. In the present study, the ability to propagate equine viruses was compared between FHK-Tcl3.1 cells and other equine cells. FHK-Tcl3.1 cells efficiently increased many viruses derived from or having pathogenicity to horses and produced high infective titers in culture fluids. These results indicate that FHK-Tcl3.1 cells would be useful for propagation and serological tests of viruses that affect Equidae.

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