Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Apr 4;18(14):20441.
doi: 10.2807/1560-7917.es2013.18.14.20441.

Specific serology for emerging human coronaviruses by protein microarray

C Reusken  1 , H Mou, G J Godeke, L van der Hoek, B Meyer, M A Müller, B Haagmans, R de Sousa, N Schuurman, U Dittmer, P Rottier, A Osterhaus, C Drosten, B J Bosch, M Koopmans
Affiliations
Free article

Specific serology for emerging human coronaviruses by protein microarray

C Reusken et al. Euro Surveill. .
Free article

Abstract

We present a serological assay for the specific detection of IgM and IgG antibodies against the emerging human coronavirus hCoV-EMC and the SARS-CoV based on protein microarray technology. The assay uses the S1 receptor-binding subunit of the spike protein of hCoV-EMC and SARS-CoV as antigens. The assay has been validated extensively using putative cross-reacting sera of patient cohorts exposed to the four common hCoVs and sera from convalescent patients infected with hCoV-EMC or SARS-CoV.

PubMed Disclaimer

Publication types