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. 2013 May;61(5):943-7.
doi: 10.1161/HYPERTENSIONAHA.111.00612.

Diabetes mellitus and vascular disease

James R Sowers  1
Affiliations

Diabetes mellitus and vascular disease

James R Sowers. Hypertension. 2013 May.

Abstract

Two-thirds of American adults are overweight or obese, 75 million have hypertension and another 25 million have diabetes. Cardiovascular disease is the leading cause of morbidity and mortality and a major driver of health care costs in patients with type 2 diabetes. Observational studies suggest that insulin resistance, hypertension and hyperglycemia independently predict cardiovascular disease and chronic kidney disease. Indeed, coexisting hypertension appears to be a most powerful determinant of cardiovascular disease risk in diabetic patients. This update explores recent investigation which sheds light on our understanding of various metabolic and hemodynamic factors which promote vascular disease, as well as strategies to lessen cardiovascular disease in patients with diabetes.

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Figures

Fig 1
Fig 1. Diabetes, Hypertension and Cardiovascular Disease
Systemic and metabolic factors that promote co-existent diabetes, hypertension, cardiovascular and chronic kidney disease.
See this image and copyright information in PMC

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