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. 2013 May 1;135(17):6419-22.
doi: 10.1021/ja401867b. Epub 2013 Apr 19.

Catalytic, enantioselective, intramolecular carbosulfenylation of olefins

Scott E Denmark  1 , Alex Jaunet
Affiliations

Catalytic, enantioselective, intramolecular carbosulfenylation of olefins

Scott E Denmark et al. J Am Chem Soc. .

Abstract

The first catalytic, enantioselective carbosulfenylation of alkenes with an aromatic nucleophile is described, using a BINAM-based selenophosphoramide catalyst. E-Alkyl- and aryl-substituted alkenes afforded tetrahydronaphthalenes with complete diastereospecificity, and generally high enantiomeric ratios.

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Figures

Scheme 1
Scheme 1
Scheme 2
Scheme 2
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