Regulatory T cells: the thymic medulla - a cradle for TReg cell development

Comment

Olive Leavy. Nat Rev Immunol. 2013 May.

. 2013 May;13(5):304.

doi: 10.1038/nri3453. Epub 2013 Apr 19.

No abstract available

Comment on

The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development.
Cowan JE, Parnell SM, Nakamura K, Caamano JH, Lane PJ, Jenkinson EJ, Jenkinson WE, Anderson G. Cowan JE, et al. J Exp Med. 2013 Apr 8;210(4):675-81. doi: 10.1084/jem.20122070. Epub 2013 Mar 25. J Exp Med. 2013. PMID: 23530124 Free PMC article.
Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway.
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