Clinical and economical impact of multiplex respiratory virus assays

doi:10.1016/j.diagmicrobio.2013.03.008

Review

. 2013 Jul;76(3):255-61.

doi: 10.1016/j.diagmicrobio.2013.03.008. Epub 2013 Apr 17.

Clinical and economical impact of multiplex respiratory virus assays

Emilie Vallières¹, Christian Renaud

Affiliations

PMID: 23601453
PMCID: PMC7132665
DOI: 10.1016/j.diagmicrobio.2013.03.008

Review

Clinical and economical impact of multiplex respiratory virus assays

Emilie Vallières et al. Diagn Microbiol Infect Dis. 2013 Jul.

. 2013 Jul;76(3):255-61.

doi: 10.1016/j.diagmicrobio.2013.03.008. Epub 2013 Apr 17.

Authors

Emilie Vallières¹, Christian Renaud

Affiliation

¹ Département de Microbiologie et Immunologie, CHU Sainte-Justine, Université de Montréal, Montréal, Québec H3T 1C5, Canada.

PMID: 23601453
PMCID: PMC7132665
DOI: 10.1016/j.diagmicrobio.2013.03.008

Abstract

During the last decade, a variety of molecular assays targeting respiratory viruses have been developed and commercialized. Therefore, multiplex PCR are increasingly used in everyday clinical practice. This improves our understanding of respiratory virus epidemiology and enhances our concerns about their clinical impact in specific patient populations. However, questions remain regarding cost-effectiveness of performing these diagnostic tests in routine and their real impact on patient care. This article will review available data and highlight unresolved questions about cost-effectiveness, infection control, clinical utility and public health impact of multiplex respiratory virus assays.

PubMed Disclaimer

Cited by

Prevalence and clinical course of upper airway respiratory virus infection in critically ill patients with hematologic malignancies.
Lee J, Kim SC, Rhee CK, Lee J, Lee JW, Lee DG. Lee J, et al. PLoS One. 2021 Dec 14;16(12):e0260741. doi: 10.1371/journal.pone.0260741. eCollection 2021. PLoS One. 2021. PMID: 34905565 Free PMC article.
Molecular Diagnosis of Pneumonia Using Multiplex Real-Time PCR Assay RespiFinder® SMART 22 FAST in a Group of Moroccan Infants.
Hattoufi K, Tligui H, Obtel M, El Ftouh S, Kharbach A, Barkat A. Hattoufi K, et al. Adv Virol. 2020 Feb 18;2020:6212643. doi: 10.1155/2020/6212643. eCollection 2020. Adv Virol. 2020. PMID: 32148499 Free PMC article.
Detection of 12 respiratory viruses by duplex real time PCR assays in respiratory samples.
Arvia R, Corcioli F, Ciccone N, Della Malva N, Azzi A. Arvia R, et al. Mol Cell Probes. 2015 Dec;29(6):408-413. doi: 10.1016/j.mcp.2015.08.006. Epub 2015 Aug 31. Mol Cell Probes. 2015. PMID: 26334289 Free PMC article.
Necessity to critically review the automatic results of the Xpert Flu assay.
Engelmann I, Alidjinou EK, Lazrek M, Dewilde A, Hober D. Engelmann I, et al. Diagn Microbiol Infect Dis. 2017 May;88(1):26-30. doi: 10.1016/j.diagmicrobio.2017.01.015. Epub 2017 Feb 2. Diagn Microbiol Infect Dis. 2017. PMID: 28214222 Free PMC article.
Evaluation of a multiplex PCR assay for detection of respiratory viruses and Mycoplasma pneumoniae in oropharyngeal swab samples from outpatients.
Zhang Y, Cao L, Xu Z, Zhu P, Huang B, Li K, Xu Y, Zhang Z, Wu Y, Di B. Zhang Y, et al. J Clin Lab Anal. 2020 Jan;34(1):e23032. doi: 10.1002/jcla.23032. Epub 2019 Oct 19. J Clin Lab Anal. 2020. PMID: 31628684 Free PMC article.

See all "Cited by" articles

References

1. Abad C., Fearday A., Safdar N. Adverse effects of isolation in hospitalised patients: a systematic review. J Hosp Infect. 2010;76(2):97–102. - PMC - PubMed
1. Abanses J.C., Dowd M.D., Simon S.D., Sharma V. Impact of rapid influenza testing at triage on management of febrile infants and young children. Pediatr Emerg Care. 2006;22(3):145–149. - PubMed
1. Aberle J.H., Aberle S.W., Pracher E., Hutter H.P., Kundi M., Popow-Kraupp T. Single versus dual respiratory virus infections in hospitalized infants: impact on clinical course of disease and interferon-gamma response. Pediatr Infect Dis J. 2005;24(7):605–610. - PubMed
1. Achonu C., Laporte A., Gardam M.A. The financial impact of controlling a respiratory virus outbreak in a teaching hospital: lessons learned from SARS. Can J Public Health. 2005;96(1):52–54. - PMC - PubMed
1. Armstrong D., Grimwood K., Carlin J.B., Carzino R., Hull J., Olinsky A. Severe viral respiratory infections in infants with cystic fibrosis. Pediatr Pulmonol. 1998;26(6):371–379. - PubMed

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
Other Literature Sources
- scite Smart Citations

[1] Abad C., Fearday A., Safdar N. Adverse effects of isolation in hospitalised patients: a systematic review. J Hosp Infect. 2010;76(2):97–102. - PMC - PubMed

[2] Abad C., Fearday A., Safdar N. Adverse effects of isolation in hospitalised patients: a systematic review. J Hosp Infect. 2010;76(2):97–102. - PMC - PubMed

[3] Abanses J.C., Dowd M.D., Simon S.D., Sharma V. Impact of rapid influenza testing at triage on management of febrile infants and young children. Pediatr Emerg Care. 2006;22(3):145–149. - PubMed

[4] Abanses J.C., Dowd M.D., Simon S.D., Sharma V. Impact of rapid influenza testing at triage on management of febrile infants and young children. Pediatr Emerg Care. 2006;22(3):145–149. - PubMed

[5] Aberle J.H., Aberle S.W., Pracher E., Hutter H.P., Kundi M., Popow-Kraupp T. Single versus dual respiratory virus infections in hospitalized infants: impact on clinical course of disease and interferon-gamma response. Pediatr Infect Dis J. 2005;24(7):605–610. - PubMed

[6] Aberle J.H., Aberle S.W., Pracher E., Hutter H.P., Kundi M., Popow-Kraupp T. Single versus dual respiratory virus infections in hospitalized infants: impact on clinical course of disease and interferon-gamma response. Pediatr Infect Dis J. 2005;24(7):605–610. - PubMed

[7] Achonu C., Laporte A., Gardam M.A. The financial impact of controlling a respiratory virus outbreak in a teaching hospital: lessons learned from SARS. Can J Public Health. 2005;96(1):52–54. - PMC - PubMed

[8] Achonu C., Laporte A., Gardam M.A. The financial impact of controlling a respiratory virus outbreak in a teaching hospital: lessons learned from SARS. Can J Public Health. 2005;96(1):52–54. - PMC - PubMed

[9] Armstrong D., Grimwood K., Carlin J.B., Carzino R., Hull J., Olinsky A. Severe viral respiratory infections in infants with cystic fibrosis. Pediatr Pulmonol. 1998;26(6):371–379. - PubMed

[10] Armstrong D., Grimwood K., Carlin J.B., Carzino R., Hull J., Olinsky A. Severe viral respiratory infections in infants with cystic fibrosis. Pediatr Pulmonol. 1998;26(6):371–379. - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Clinical and economical impact of multiplex respiratory virus assays

Affiliation

Clinical and economical impact of multiplex respiratory virus assays

Authors

Affiliation

Abstract

Similar articles

Cited by

References

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

Abstract

Similar articles

Cited by

References

Publication types

MeSH terms

Related information

LinkOut - more resources

Full Text Sources

Other Literature Sources