Dysfunctional HDL takes its toll in chronic kidney disease
- PMID: 23601680
- DOI: 10.1016/j.immuni.2013.03.006
Dysfunctional HDL takes its toll in chronic kidney disease
Abstract
Why patients with chronic kidney disease have elevated cardiovascular risk remains elusive. In this issue of Immunity, Speer et al. (2013) show that natural modification of high density lipoprotein promotes hypertension through a Toll-like receptor-dependent mechanism.
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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Abnormal high-density lipoprotein induces endothelial dysfunction via activation of Toll-like receptor-2.Immunity. 2013 Apr 18;38(4):754-68. doi: 10.1016/j.immuni.2013.02.009. Epub 2013 Mar 7. Immunity. 2013. PMID: 23477738
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