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. 1990 May;34(5):909-10.
doi: 10.1128/AAC.34.5.909.

Fluconazole levels in plasma and vaginal secretions of patients after a 150-milligram single oral dose and rate of eradication of infection in vaginal candidiasis

E T Houang  1 , O Chappatte, D Byrne, P V Macrae, J E Thorpe
Affiliations

Fluconazole levels in plasma and vaginal secretions of patients after a 150-milligram single oral dose and rate of eradication of infection in vaginal candidiasis

E T Houang et al. Antimicrob Agents Chemother. 1990 May.

Abstract

Mean peak concentrations of fluconazole in plasma and vaginal secretions of females after a 150-mg single oral dose were shown to be 2.82 micrograms/ml and 2.43 micrograms/g, respectively. Our results indicate that clinically efficacious concentrations of fluconazole in vaginal secretions are easily achieved after this single oral dose.

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