How ageing processes influence cancer
- PMID: 23612461
- DOI: 10.1038/nrc3497
How ageing processes influence cancer
Abstract
The ageing of populations worldwide is leading to an unprecedented increase in cancer cases and fatalities. Understanding the links between cancer and ageing is therefore more important than ever. How the interplay of ageing-associated changes affects cancer initiation and progression is complex, however, and some ageing processes probably foster cancer development whereas others hinder it, possibly in a tissue-specific manner. In the emerging age of cancer, how can our growing understanding of the biology of ageing inform cancer biology?
Similar articles
-
Dietary restriction mitigates age-related accumulation of DNA damage, but not all changes in mouse corneal epithelium.Exp Gerontol. 2015 Jul;67:72-9. doi: 10.1016/j.exger.2015.04.014. Epub 2015 Apr 30. Exp Gerontol. 2015. PMID: 25937374
-
Cancer-free aging: Insights from Spalax ehrenbergi superspecies.Ageing Res Rev. 2018 Nov;47:18-23. doi: 10.1016/j.arr.2018.06.004. Epub 2018 Jun 15. Ageing Res Rev. 2018. PMID: 29913210 Review.
-
Reflections on telomere dynamics and ageing-related diseases in humans.Philos Trans R Soc Lond B Biol Sci. 2018 Mar 5;373(1741):20160436. doi: 10.1098/rstb.2016.0436. Philos Trans R Soc Lond B Biol Sci. 2018. PMID: 29335375 Free PMC article.
-
Cancer and normal ageing.Mech Ageing Dev. 1984 Jun;25(3):269-83. doi: 10.1016/0047-6374(84)90001-0. Mech Ageing Dev. 1984. PMID: 6376965 Review.
-
Biology of cancer and ageing.Eur J Cancer. 2009 Sep;45 Suppl 1:414-5. doi: 10.1016/S0959-8049(09)70070-X. Eur J Cancer. 2009. PMID: 19775652 No abstract available.
Cited by
-
Spectrum and Trends of Cancer in Southwestern Uganda from 2012 to 2021.East Afr Health Res J. 2024;8(1):32-42. doi: 10.24248/eahrj.v8i1.746. Epub 2024 Mar 28. East Afr Health Res J. 2024. PMID: 39234344 Free PMC article.
-
Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina.J Biol Chem. 2015 Jun 26;290(26):16415-30. doi: 10.1074/jbc.M115.660829. Epub 2015 May 15. J Biol Chem. 2015. PMID: 25979334 Free PMC article.
-
Cancer cachexia: biomarkers and the influence of age.Mol Oncol. 2024 Sep;18(9):2070-2086. doi: 10.1002/1878-0261.13590. Epub 2024 Feb 27. Mol Oncol. 2024. PMID: 38414161 Free PMC article. Review.
-
Surtuin 1 as a potential prognostic biomarker in very elderly patients with colorectal cancer.Korean J Intern Med. 2021 Mar;36(Suppl 1):S235-S244. doi: 10.3904/kjim.2019.249. Epub 2020 Jul 2. Korean J Intern Med. 2021. PMID: 32605336 Free PMC article.
-
Type I collagen aging impairs discoidin domain receptor 2-mediated tumor cell growth suppression.Oncotarget. 2016 May 3;7(18):24908-27. doi: 10.18632/oncotarget.8795. Oncotarget. 2016. PMID: 27121132 Free PMC article.
References
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Molecular Biology Databases