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. 2014 May;20(4):393-9.
doi: 10.1177/1076029613485283. Epub 2013 Apr 23.

Carotid intima-media thickness in patients with slow coronary flow and its association with neutrophil-to-lymphocyte ratio: a preliminary report

Faruk Cingoz  1 , Atila Iyisoy, Sait Demirkol, Mehmet Ali Sahin, Sevket Balta, Turgay Celik, Murat Unlu, Zekeriya Arslan, Mustafa Cakar, Ugur Kucuk, Seref Demirbas, Necmettin Kocak
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Free article

Carotid intima-media thickness in patients with slow coronary flow and its association with neutrophil-to-lymphocyte ratio: a preliminary report

Faruk Cingoz et al. Clin Appl Thromb Hemost. 2014 May.
Free article

Abstract

Background: The slow coronary flow (SCF) is characterized by angiographically normal or near-normal coronary arteries with delayed progression of the contrast agent into distal vasculature. We aimed to investigate neutrophil-to-lymphocyte (N/L) ratio and the carotid intima-media thickness (CIMT) value in patients with SCF compared to patients with newly diagnosed coronary artery disease (CAD) and normal patients.

Materials and methods: We enrolled 60 consecutive patients with SCF, 68 patients with CAD, and 72 normal patients. The association between thrombolysis in myocardial infarction frame count, CIMT, and N/L ratio and other clinical and laboratory parameters were evaluated.

Results: The N/L ratio was significantly higher not only in patients with SCF but also in patients with CAD, compared to those of controls. The N/L ratio was positively and moderately correlated with CIMT in the whole study population.

Conclusions: The NL ratio is significantly associated with reduced coronary blood flow, and elevated N/L ratio might be an independent predictor for the presence of SCF.

Keywords: carotid intima-media thickness; neutrophil-to-lymphocyte ratio; slow coronary flow.

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