Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2013 Apr 25:13:389.
doi: 10.1186/1471-2458-13-389.

BMI mediates the association between low educational level and higher blood pressure during pregnancy in Japan

Affiliations
Comparative Study

BMI mediates the association between low educational level and higher blood pressure during pregnancy in Japan

Seung Chik Jwa et al. BMC Public Health. .

Abstract

Background: Research investigating the association between socioeconomic status (SES) and blood pressure (BP) during pregnancy is limited and its underlying pathway is unknown. The aim of this study was to investigate the mediators of the association between educational level as an indicator of the SES and BP in early and mid-pregnancy among Japanese women.

Methods: Nine hundred and twenty-three pregnant women in whom BP was measured before 16 weeks and at 20 weeks of gestation were enrolled in this study. Maternal educational levels were categorized into three groups: high (university or higher), mid (junior college), and low (junior high school, high school, or vocational training school).

Results: The low educational group had higher systolic (low vs. high, difference = 2.39 mmHg, 95% confidence interval [CI]: 0.59 to 4.19) and diastolic BP levels (low vs. high, difference = 0.74 mmHg, 95% CI: -0.52 to 1.99) in early pregnancy. However, the same associations were not found after adjustment for pre-pregnancy body mass index (BMI). BP reduction was observed in mid-pregnancy in all three educational groups and there was no association between educational level and pregnancy-induced hypertension.

Conclusion: In Japanese women, the low educational group showed higher BP during pregnancy than the mid or high educational groups. Pre-pregnancy BMI mediates the association between educational level and BP.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Mean systolic blood pressure in early, mid-pregnancy stratified by educational level. Mean blood pressure was significantly different from that in subgroup of women with low (*) and mid (**) educational level (P<0.05).
Figure 2
Figure 2
Mean diastolic blood pressure in early, mid-pregnancy stratified by educational level. Mean blood pressure was not significantly different from that in subgroup of women with low and mid educational level (P<0.05).

References

    1. Churchill D, Perry IJ, Beevers DG. Ambulatory blood pressure in pregnancy and fetal growth. Lancet. 1997;349(9044):7–10. doi: 10.1016/S0140-6736(96)06297-6. - DOI - PubMed
    1. Waugh J, Perry IJ, Halligan AW, De Swiet M, Lambert PC, Penny JA, Taylor DJ, Jones DR, Shennan A. Birth weight and 24-hour ambulatory blood pressure in nonproteinuric hypertensive pregnancy. Am J Obstet Gynecol. 2000;183(3):633–637. doi: 10.1067/mob.2000.106448. - DOI - PubMed
    1. Poon LC, Kametas NA, Pandeva I, Valencia C, Nicolaides KH. Mean arterial pressure at 11(+0) to 13(+6) weeks in the prediction of preeclampsia. Hypertension. 2008;51(4):1027–1033. doi: 10.1161/HYPERTENSIONAHA.107.104646. - DOI - PubMed
    1. Cnossen JS, Vollebregt KC, de Vrieze N, ter Riet G, Mol BW, Franx A, Khan KS, van der Post JA. Accuracy of mean arterial pressure and blood pressure measurements in predicting pre-eclampsia: systematic review and meta-analysis. BMJ. 2008;336(7653):1117–1120. doi: 10.1136/bmj.39540.522049.BE. - DOI - PMC - PubMed
    1. Schroeder BM. ACOG practice bulletin on diagnosing and managing preeclampsia and eclampsia. American college of obstetricians and gynecologists. Am Fam Physician. 2002;66(2):330–331. - PubMed

Publication types