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. 2013 Jul;67(7):606-18.
doi: 10.1111/ijcp.12176. Epub 2013 Apr 25.

Erectile dysfunction and lower urinary tract symptoms: a consensus on the importance of co-diagnosis

M Kirby  1 , C Chapple, G Jackson, I Eardley, D Edwards, G Hackett, D Ralph, J Rees, M Speakman, J Spinks, K Wylie
Affiliations
Free PMC article

Erectile dysfunction and lower urinary tract symptoms: a consensus on the importance of co-diagnosis

M Kirby et al. Int J Clin Pract. 2013 Jul.
Free PMC article

Abstract

Despite differences in design, many large epidemiological studies using well-powered multivariate analyses consistently provide overwhelming evidence of a link between erectile dysfunction (ED) and lower urinary tract symptoms (LUTS). Preclinical evidence suggests that several common pathophysiological mechanisms are involved in the development of both ED and LUTS. We recommend that patients seeking consultation for one condition should always be screened for the other condition. We propose that co-diagnosis would ensure that patient management accounts for all possible co-morbid and associated conditions. Medical, socio-demographic and lifestyle risk factors can help to inform diagnoses and should be taken into consideration during the initial consultation. Awareness of risk factors may alert physicians to patients at risk of ED or LUTS and so allow them to manage patients accordingly; early diagnosis of ED in patients with LUTS, for example, could help reduce the risk of subsequent cardiovascular disease. Prescribing physicians should be aware of the sexual adverse effects of many treatments currently recommended for LUTS; sexual function should be evaluated prior to commencement of treatment, and monitored throughout treatment to ensure that the choice of drug is appropriate.

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Figures

Figure 1
Figure 1
Erectile dysfunction according to age and lower urinary tract symptoms severity (30)
Figure 2
Figure 2
Potential pathophysiological pathways leading to lower urinary tract symptoms in men (Adapted from Refs (27,33))
Figure 3
Figure 3
Co-diagnosis algorithm for erectile dysfunction and lower urinary tract symptoms
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Comment in

  • Peanut butter and jelly.
    Rosenberg MT. Rosenberg MT. Int J Clin Pract. 2013 Jul;67(7):599-600. doi: 10.1111/ijcp.12203. Int J Clin Pract. 2013. PMID: 23758440 No abstract available.

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