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Case Reports
. 1990 Jun;29(5):375-6.
doi: 10.1111/j.1365-4362.1990.tb04768.x.

Treatment of sickle cell leg ulcers with pentoxifylline

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Case Reports

Treatment of sickle cell leg ulcers with pentoxifylline

M L Frost et al. Int J Dermatol. 1990 Jun.

Abstract

A 58-year-old black man with leg ulcers of 43 years duration responded to pentoxifylline 400 mg tid in 8 months. The ability of pentoxifylline to increase erythrocyte flexibility and decrease blood viscosity was the basis for our use of this agent. Oral pentoxifylline may be a useful adjunct in healing sickle cell leg ulcers and preventing their recurrence.

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