Thoracic phosphaturic mesenchymal tumors causing oncogenic osteomalacia

Abstract

Oncogenic osteomalacia is a rare paraneoplastic syndrome induced by mesenchymal tumors. Just over 100 cases have been reported for this rare disorder, and only seven instances were caused by phosphaturic mesenchymal tumors of the spine. The authors present an illustrative case of a 61-year-old woman with oncogenic osteomalacia induced by a tumor of the spine, and review the literature describing the clinical presentation, surgical treatment, and follow-up of this syndrome.

Keywords: Fibroblast growth factor; Hypophosphatemia; Oncogenic osteomalacia; Paraneoplastic syndrome; Phosphaturic mesenchymal tumor; Thoracic spine.