Relation between platelet indices and branch retinal vein occlusion in hypertensive patients
- PMID: 23619481
- PMCID: PMC3714952
- DOI: 10.4103/0301-4738.111063
Relation between platelet indices and branch retinal vein occlusion in hypertensive patients
Abstract
Background: Branch retinal vein occlusion (BRVO) is the second most common retinal vascular disease after diabetic retinopathy. To date, the studies were unable to elucidate the mechanism of the thrombosis leading to the entity; particularly the relation between thrombocyte aggregation and retinal vein occlusion is still unclear. Mean platelet volume (MPV) is a determinant of rate of platelet production and activation, both of which are indices of function of platelets. The relation between MPV and BRVO has not been studied before. The aim was to evaluate MPV in BRVO.
Materials and methods: Forty patients were included in the study. Forty six age and sex matched hypertensive volunteers were recruited as the control group.
Results: MPV values were significantly higher in BRVO patients compared with the control subjects (8.01 ± 0.79 vs 7.52 ± 0.32 fL, respectively; P < 0.001).
Conclusion: MPV is significantly higher in patients hypertensive BRVO patients and further investigations regarding its potentially use as a prognostic biomarker in patients with BRVO are needed.
Conflict of interest statement
Comment in
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Mean platelet volume as a marker of branch retinal vein occlusion may be influenced by many factors.Indian J Ophthalmol. 2013 Nov;61(11):686-7. doi: 10.4103/0301-4738.119414. Indian J Ophthalmol. 2013. PMID: 24145568 Free PMC article. No abstract available.
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The neutrophil lymphocyte ratio may be useful inflammatory indicator before applying other expensive and invasive procedures.Indian J Ophthalmol. 2013 Nov;61(11):685. doi: 10.4103/0301-4738.123150. Indian J Ophthalmol. 2013. PMID: 24343599 Free PMC article. No abstract available.
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Platelet indices in retinal vein occlusion in hypertensive patients.Indian J Ophthalmol. 2013 Nov;61(11):692. doi: 10.4103/0301-4738.121136. Indian J Ophthalmol. 2013. PMID: 24343602 Free PMC article. No abstract available.
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Authors' reply.Indian J Ophthalmol. 2014 Jan;62(1):96-7. doi: 10.4103/0301-4738.126195. Indian J Ophthalmol. 2014. PMID: 24654271 Free PMC article. No abstract available.
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