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. 2013 Jul 1;29(13):1679-81.
doi: 10.1093/bioinformatics/btt198. Epub 2013 Apr 25.

RSVSim: an R/Bioconductor package for the simulation of structural variations

Christoph Bartenhagen  1 , Martin Dugas
Affiliations

RSVSim: an R/Bioconductor package for the simulation of structural variations

Christoph Bartenhagen et al. Bioinformatics. .

Abstract

RSVSim is a tool for the simulation of deletions, insertions, inversions, tandem duplications and translocations of various sizes in any genome available as FASTA-file or data package in R. The structural variations can be generated randomly, based on user-supplied genomic coordinates or associated to various kinds of repeats. The package further comprises functions to estimate the distribution of structural variation sizes from real datasets.

Availability: RSVSim is implemented in R and available at http://www.bioconductor.org. A vignette with detailed descriptions of the functions and examples is included.

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