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. 2013 Apr;3(4):315-24.
doi: 10.1016/S2221-1691(13)60071-4.

Surveillance of multidrug resistant uropathogenic bacteria in hospitalized patients in Indian

Monali Priyadarsini Mishra  1 , Nagen Kumar Debata, Rabindra Nath Padhy
Affiliations

Surveillance of multidrug resistant uropathogenic bacteria in hospitalized patients in Indian

Monali Priyadarsini Mishra et al. Asian Pac J Trop Biomed. 2013 Apr.

Abstract

Objective: To record surveillance, antibiotic resistance of uropathogens of hospitalized patients over a period of 18 months.

Methods: Urine samples from wards and cabins were used for isolating urinary tract infection (UTI)-causing bacteria that were cultured on suitable selective media and identified by biochemical tests; and their antibiograms were ascertained by Kirby-Bauer's disc diffusion method, in each 6-month interval of the study period, using 18 antibiotics of five different classes.

Results: From wards and cabins, 1 245 samples were collected, from which 996 strains of bacteria belonging to 11 species were isolated, during April 2011 to September 2012. Two Gram-positive, Staphylococcus aureus (S. aureus) and Enterococcus faecalis (E. faecalis), and nine Gram-negative bacteria, Acinetobacter baumannii, Citrobacter sp., Escherichia coli, Enterobacter aerogenes, Klebsiella pneumoniae, Klebsiella oxytoca, Proteus mirabilis, Proteus vulgaris and Pseudomonas aeruginosa were isolated. Both S. aureus and E. faecalis were vancomycin resistant, and resistant-strains of all pathogens increased in each 6-month period of study. Particularly, all Gram-negatives were resistant to nitrofurantoin and co-trimoxazole, the most preferred antibiotics of empiric therapy for UTI.

Conclusions: Antibiograms of 11 UTI-causing bacteria recorded in this study indicated moderately higher numbers of strains resistant to each antibiotic studied, generating the fear of precipitating fervent episodes in public health particularly with bacteria, Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae and S. aureus. Moreover, vancomycin resistance in strains of S. aureus and E. faecalis is a matter of concern.

Keywords: Acinetobacter baumannii; Antibiograms; Antibiotics; Escherichia coli; Hospitalized patients; Klebsiella pneumoniae; MDR bacteria; Nosocomial infections; Staphylococcus aureus; UTI.

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Conflict of interest statement

Conflict of interest statement: The authors declare that they have no conflict of interests.

Figures

Figure 1.
Figure 1.. Translucent blue colonies of E. coli on CLED agar.
See this image and copyright information in PMC

References

    1. Drekonja DM, Johnson JR. Urinary tract infections. Prim Care. 2008;35:345–367. - PubMed
    1. Taneja N, Chatterjee SS, Singh M, Singh S, Sharma M. Pediatric urinary tract infections in a tertiary care center from Northern India. Indian J Med Res. 2010;131:101–105. - PubMed
    1. Jeyaseelan EC, Jashothan PT. In vitro control of Staphylococcus aureus (NCTC 6571) and Escherichia coli (ATCC 25922) by Ricinus communis L. Asian Pac J Trop Biomed. 2012;2(9):717–721. - PMC - PubMed
    1. Behzadi P, Behzadi E, Yazdanbod H. Urinary tract infections associated with Candida albicans. Maedica. 2010;5:277–279. - PMC - PubMed
    1. Kawecki D, Kwiatkowski A, Sawicka-Grzelak A, Durlik M, Paczek L, Chmura A, et al. et al. Urinary tract infections in the early post transplant period after kidney transplantation: etiologic agents and their susceptibility. Transplant Proc. 2011;43:2991–2993. - PubMed

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