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. 2013 Mar;19(3):485-7.
doi: 10.3201/eid1902.120527.

Tuberculosis outbreak in a primary school, Milan, Italy

Marino Faccini  1 , Luigi Ruffo Codecasa, Giorgio Ciconali, Serafina Cammarata, Catia Rosanna Borriello, Costanza De Gioia, Alessandro Za, Andrea Filippo Marino, Valentina Vighi, Maurizio Ferrarese, Giovanni Gesu, Ester Mazzola, Silvana Castaldi
Affiliations

Tuberculosis outbreak in a primary school, Milan, Italy

Marino Faccini et al. Emerg Infect Dis. 2013 Mar.

Abstract

Investigation of an outbreak of tuberculosis (TB) in a primary school in Milan, Italy, found 15 schoolchildren had active TB disease and 173 had latent TB infection. TB was also identified in 2 homeless men near the school. Diagnostic delay, particularly in the index case-patient, contributed to the transmission of infection.

Keywords: Beijing strain; Italy; Milan; bacteria; children; control; diagnosis; disease management; epidemiology; genotyping; homeless; outbreak; school; surveillance; tuberculosis; tuberculosis and other mycobacteria.

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Figures

Figure 1
Figure 1
Floor plan of classrooms at primary school in Milan, Italy, 2010. Values are no. tuberculosis infections/total no. pupils in classroom (% pupils infected). Shading indicates classrooms with highest rates of infection: the classroom of the 17-year-old student determined to be the index case-patient (black shading) and the 2 adjacent classrooms (gray shading).
Figure 2
Figure 2
Hypothetical timeline of tuberculosis (TB) outbreak at primary school in Milan, Italy, 2009–2011. Vertical dashed lines indicate school year delineation. The connection among cases established through epidemiologic investigation (epi) or genotyping of Mycobacterium tuberculosis strains (gen) is indicated.
See this image and copyright information in PMC

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