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Comment
. 2013 Apr 25;50(2):159-60.
doi: 10.1016/j.molcel.2013.04.009.

Catching the waves: following the leading edge of elongating RNA polymerase II

Telmo Henriques  1 , Karen Adelman
Affiliations
Comment

Catching the waves: following the leading edge of elongating RNA polymerase II

Telmo Henriques et al. Mol Cell. .

Abstract

By precisely tracking the waves of elongating RNA polymerase II (Pol II) during gene activation, Danko et al. (2013), in this issue of Molecular Cell, discovered a surprising diversity of elongation rates among and along human genes.

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Figures

Figure 1
Figure 1
Defining the waves of transcription elongation on endogenous genes under different activating conditions. (A) Using GRO-seq to map Pol II distribution at different time points following gene activation. (B) The observed elongation rate is linked to the basal activity level of a gene, with higher expression levels in uninduced cells correlating with faster elongation rates during gene activation.
See this image and copyright information in PMC

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References

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