Signaling pathways mediating adhesion and spreading through extracellular ADP and the P2Y12 receptor: presented by Maria P. Abbracchio
- PMID: 23624893
- PMCID: PMC3646117
- DOI: 10.1007/s11302-013-9363-6
Signaling pathways mediating adhesion and spreading through extracellular ADP and the P2Y12 receptor: presented by Maria P. Abbracchio
Comment on
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β-arrestin 2-dependent activation of ERK1/2 is required for ADP-induced paxillin phosphorylation at Ser(83) and microglia chemotaxis.Glia. 2012 Sep;60(9):1366-77. doi: 10.1002/glia.22355. Epub 2012 May 25. Glia. 2012. PMID: 22638989 Free PMC article.
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The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling.J Clin Invest. 2012 Oct;122(10):3579-92. doi: 10.1172/JCI38576. Epub 2012 Sep 17. J Clin Invest. 2012. PMID: 22996695 Free PMC article.
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References
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- Kauffenstein G, Bergmeier W, Eckly A, Ohlmann P, Leon C, Cazenave JP, Nieswandt B, Gachet C. The P2Y(12) receptor induces platelet aggregation through weak activation of the alpha(IIb)beta(3) integrin–a phosphoinositide 3-kinase-dependent mechanism. FEBS Lett. 2001;505:281–290. doi: 10.1016/S0014-5793(01)02824-1. - DOI - PubMed
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