Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Sep;32(9):962-4.
doi: 10.1097/INF.0b013e318298dfb8.

Optimization of continuous infusion of piperacillin-tazobactam in children with fever and neutropenia

Mélanie Delvallée  1 , Françoise Mazingue, Wadi Abouchahla, Mathilde Delebarre, Frédéric Wallet, René Courcol, Eric Kipnis, Rodrigue Dessein
Affiliations

Optimization of continuous infusion of piperacillin-tazobactam in children with fever and neutropenia

Mélanie Delvallée et al. Pediatr Infect Dis J. 2013 Sep.

Abstract

The study through Monte Carlo simulation of β-lactam pharmacokinetic/pharmacodynamic target attainment and determination of subsequent serum concentrations of piperacillin-tazobactam administered through continuous infusion to children treated for fever and neutropenia shows that 400 mg/kg/day has the highest probability of target attainment against Pseudomonas aeurginosa in our oncology ward compared with the standard regimen of 300 mg/kg/day.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources