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. 2013 Apr 30:8:118.
doi: 10.1186/1749-8090-8-118.

Risk factors for postoperative hypoxemia in patients undergoing Stanford A aortic dissection surgery

Yinghua Wang, Song Xue, Hongsheng Zhu

Risk factors for postoperative hypoxemia in patients undergoing Stanford A aortic dissection surgery

Yinghua Wang et al. J Cardiothorac Surg. .

Abstract

Background: The purpose of this study is to identify the risk factors for postoperative hypoxemia in patients with Stanford A aortic dissection surgery and their relation to clinical outcomes.

Methods: Clinical records of 186 patients with postoperative hypoxemia in Stanford A aortic dissection were analyzed retrospectively. The patients were divided into two groups by postoperative oxygen fraction (PaO2/FiO2):hypoxemia group (N=92) and non-hypoxemia group (N=94).

Results: We found that the incidence of postoperative hypoxemia was 49.5%. Statistical analysis by t-test and χ2 indicated that acute onset of the aortic dissection (p=0.000), preoperative oxygen fraction (PaO2/FiO2) ≤200 mmHg(p=0.000), body mass index (p=0.008), circulatory arrest (CA) time (p=0.000) and transfusion more than 3000 ml(p=0.000) were significantly associated with postoperative hypoxemia. Multiple logistic regression analysis showed that preoperative hypoxemia, CA time and transfusion more than 3000 ml were independently associated with postoperative hypoxemia in Stanford A aortic dissection.

Conclusion: Our results suggest that postoperative hypoxemia is a common complication in patients treated by Stanford A aortic dissection surgery. Preoperative oxygen fraction lower than 200 mmHg, longer CA time and transfusion more than 3000 ml are predictors of postoperative hypoxemia in Stanford A aortic dissection.

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Figures

Figure 1
Figure 1
Kaplan-Meier survival curve.
See this image and copyright information in PMC

References

    1. Takayuki N, Kohei K, Hiroshi I, Tsuyoshi K, Hiroyuki N, Nobuo S. Risk factors for hypoxemia after surgery for acute type A aortic dissection. Surg Today. 2006;36:680–685. doi: 10.1007/s00595-006-3226-5. - DOI - PubMed
    1. Filsoufi F, Rahmanian PB, Castillo JG, Chikwe J, Adams DH. Logistic risk model predicting postoperative respiratory failure in patients undergoing valve surgery. Eur J Cardiothorac Surg. 2008;34(5):953–959. doi: 10.1016/j.ejcts.2008.07.061. - DOI - PubMed
    1. Ji Q, Mei Y, Wang X, Feng J, Cai J, Sun Y, Xie S, Li D, Dayi H. Study on the risk factors of postoperative hypoxemia in patients undergoing coronary artery bypass grafting. Circ J. 2008;72:1975–1980. doi: 10.1253/circj.CJ-08-0369. - DOI - PubMed
    1. Yende S, Wunderink R. Causes of prolonged mechanical ventilation after coronary artery bypass surgery. Chest. 2002;122:245–252. doi: 10.1378/chest.122.1.245. - DOI - PubMed
    1. Branca P, McGaw P, Light RW. Factors associated with prolonged mechanical ventilation following coronary artery bypass surgery. Chest. 2001;119:537–546. doi: 10.1378/chest.119.2.537. - DOI - PubMed