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Review
. 2013 Jul;47 Suppl(0):S2-6.
doi: 10.1097/MCG.0b013e3182872f29.

Epidemiology of hepatocellular carcinoma: consider the population

Sahil Mittal  1 , Hashem B El-Serag
Affiliations
Review

Epidemiology of hepatocellular carcinoma: consider the population

Sahil Mittal et al. J Clin Gastroenterol. 2013 Jul.

Abstract

Hepatocellular carcinoma (HCC) is increasing in incidence and has a very high fatality rate. Cirrhosis due to chronic hepatitis B or hepatitis C is the leading risk factor for HCC. Global epidemiology of HCC is determined by the prevalence of dominant viral hepatitis and the age it is acquired in the underlying population. Upcoming risk factors include obesity, diabetes, and related nonalcoholic fatty liver disease. This review discusses the latest trends of HCC globally and in the United States. It also provides an evidence-based commentary on the risk factors and lists some of the preventive measures to reduce the incidence of HCC.

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Figures

Figure 1
Figure 1
Age-standardized incidence rates of hepatocellular carcinoma per 100,000 populations at risk, in different regions of world (Source: GLOBOCAN 2002).
Figure 2
Figure 2
Age-adjusted incidence rate of hepatocellular carcinoma by race based on SEER registry data from 1975-2007.
See this image and copyright information in PMC

References

    1. GLOBOCAN International Agency for Research on Cancer (IARC) 2002 Available at: http://www-dep.iarc.fr.
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    1. Davila JA, El-Serag HB. The Rising Incidence of Hepatocellular Carcinoma in the United States: an Update. Gastroenterology. 2012;142(suppl 1):S914–S914.

MeSH terms