A balanced view of calcium and phosphate homeostasis in chronic kidney disease
- PMID: 23633052
- DOI: 10.1038/ki.2013.21
A balanced view of calcium and phosphate homeostasis in chronic kidney disease
Abstract
The association of abnormalities of calcium and phosphate homeostasis with adverse clinical outcomes in chronic kidney disease (CKD) has generated interest in developing therapeutic strategies to target mineral metabolism early in the course of CKD. Hill et al. present results from a classic balance study of CKD stage 3-4 patients that challenge existing paradigms and suggest a need to rethink our understanding of calcium and phosphate homeostasis in CKD.
Comment on
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Oral calcium carbonate affects calcium but not phosphorus balance in stage 3-4 chronic kidney disease.Kidney Int. 2013 May;83(5):959-66. doi: 10.1038/ki.2012.403. Epub 2012 Dec 19. Kidney Int. 2013. PMID: 23254903 Free PMC article. Clinical Trial.
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