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. 2013 Apr 30;110(18):7104-6.
doi: 10.1073/pnas.1306643110.

Solving tough problems with games

Mark Schrope

Solving tough problems with games

Mark Schrope. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

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Players of Phylo compare the genome sequences of many animals to find genetic segments that are similar. Copyright © 2012 McGill University. All rights reserved.
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Foldit asks players to find the most stable configurations of folded proteins, a task at which humans can beat the best computer algorithms. Image courtesy of the University of Washington, Seattle.
See this image and copyright information in PMC

References

    1. Good BM, Su AI. Games with a scientific purpose. Genome Biol. 2011;12(12):135. - PMC - PubMed
    1. Khatib F, et al. Foldit Contenders Group Foldit Void Crushers Group Crystal structure of a monomeric retroviral protease solved by protein folding game players. Nat Struct Mol Biol. 2011;18(10):1175–1177. - PMC - PubMed
    1. Khatib F, et al. Algorithm discovery by protein folding game players. Proc Natl Acad Sci USA. 2011;108(47):18949–18953. - PMC - PubMed
    1. Eiben CB, et al. Increased Diels-Alderase activity through backbone remodeling guided by Foldit players. Nat Biotechnol. 2012;30(2):190–192. - PMC - PubMed
    1. Kawrykow A, et al. Phylo players Phylo: A citizen science approach for improving multiple sequence alignment. PLoS ONE. 2012;7(3):e31362. - PMC - PubMed