Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2013 Jan;4(1):252-7.
doi: 10.4103/0976-9668.107320.

Infiltrating lipomatosis of the face: A case series

Aadithya B Urs  1 , Jeyaseelan Augustine, Priya Kumar, Shelly Arora, Neha Aggarwal, Neha Sultana
Affiliations
Case Reports

Infiltrating lipomatosis of the face: A case series

Aadithya B Urs et al. J Nat Sci Biol Med. 2013 Jan.

Abstract

Infiltrating lipomatosis of the face is a very rare entity which is characterized by the collection of non-encapsulated mature adipocytes infiltrating local tissues, resulting in craniofacial deformities. Psychomotor development of the patients is normal, esthetics often being the primary concern to seek treatment. The presentation is always unilateral with hypertrophy of hard and soft structures on the affected side of the face. The pathogenesis of the condition is unclear. This condition shows a wide phenotypic range, uncertain prognosis with high rates of recurrence after surgery, and variable post-op cosmetic improvement. The condition shows no gender predilection, with most of the cases presenting in and beyond the second decade of life. Here, we present a series of four cases presenting in varying age groups with history of recurrence in three cases.

Keywords: Hypertrophy; infiltrating; lipomatosis; recurrence.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared

Figures

Figure 1
Figure 1
(a) Extent of the swelling extraorally; (b) Intraoral swelling covering the right buccal mucosa; (c) Gross specimen; (d) Adipocytes infiltrating neurovascular bundle (H and E, ×200)
Figure 2
Figure 2
(a) Extraoral extent; (b) Contrast-enhanced computed tomography showing fatty infiltration of the buccinator, masseter, and parotid gland; (c) Gross specimen; (d) Adipocytes infiltrating the muscle (H and E, ×200)
Figure 3
Figure 3
(a) Large swelling on the left side of the face; (b) Intraoral expansion of maxillary alveolar process; (c) Adipocytes infiltrating the marrow spaces (H and E, ×200)
Figure 4
Figure 4
(a) Diffuse swelling over left cheek; (b) Magnetic resonance imaging showing fatty infiltration
See this image and copyright information in PMC

References

    1. Slavin SA, Baker DC, Mccarthy JG, Muffarrij A. Congenital infiltrating lipomatosis of the face: Clinicopathological evaluation and treatment. Plast Reconstr Surg. 1983;72:158–64. - PubMed
    1. Singh K, Sen P, Musgrove BT, Thicker N. Facial infiltrating lipomatosis: A case report and review of literature. Int J Surg Case Rep. 2011;2:201–5. - PMC - PubMed
    1. Couto RA, Mulliken JB, Padwa BL, Hassanein AH, Rogers GF, Kulungowski AM, et al. Facial infiltarting lipomatosis: Expressin of angiogenic and vasculogenic factors. J Craniofac Surg. 2011;22:2405–8. - PubMed
    1. Rajeswaran R, Musthy J, Chandrasekharan A, Joseph S. Case report: Congenital infiltrating lipomatosis of face. Indain J Radiol Imaging. 2008;18:306–9. - PMC - PubMed
    1. Heymans O, Ronsmans C. Congenital infiltrating lipomatosis of face. Eur J Plast Surg. 2005;26:186–9.

Publication types

LinkOut - more resources