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. 2013 Apr 25;7(4):e2081.
doi: 10.1371/journal.pntd.0002081. Print 2013.

Peripheral blood mononuclear cells of mycetoma patients react differently to Madurella mycetomatis antigens than healthy endemic controls

Ehab A M Elagab  1 , Maowia M Mukhtar, Ahmed H Fahal, Wendy W J van de Sande
Affiliations

Peripheral blood mononuclear cells of mycetoma patients react differently to Madurella mycetomatis antigens than healthy endemic controls

Ehab A M Elagab et al. PLoS Negl Trop Dis. .
No abstract available

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Cytokine concentrations of stimulated PBMCs of eumycetoma patients and healthy controls.
(A) IL-10 concentrations (pg/ml) measured after stimulating PBMCs from eumycetoma patients and healthy endemic controls with M. mycetomatis antigen. Statistically significantly different concentrations were found between eumycetoma patients and healthy controls (p = 0.004) as determined by the Mann–Whitney U test. (B) IFN-γ concentrations (pg/ml) measured after stimulating PBMCs from eumycetoma patients and healthy endemic controls with M. mycetomatis antigen. Statistically significantly different concentrations were found between eumycetoma patients and healthy controls (p = 0.007) as determined by the Mann–Whitney U test. (C) TNF-α concentrations (pg/ml) measured after stimulating PBMCs from eumycetoma patients and healthy endemic controls with M. mycetomatis antigen. No statistically significantly different concentrations were found between eumycetoma patients and healthy controls (p = 0.85) as determined by the Mann–Whitney U test. (D) TGF-β concentrations (pg/ml) measured after stimulating PBMCs from eumycetoma patients and healthy endemic controls with M. mycetomatis antigen. No statistically significantly different concentrations were found between eumycetoma patients and healthy controls (p = 0.89) as determined by the Mann–Whitney U test.
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