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Review
. 2013 Jun;7(2):131-8.
doi: 10.1097/SPC.0b013e3283615ebe.

Management of neuropathic pain in children with cancer

Stefan J Friedrichsdorf  1 , Andrea Postier Nugent
Affiliations
Review

Management of neuropathic pain in children with cancer

Stefan J Friedrichsdorf et al. Curr Opin Support Palliat Care. 2013 Jun.

Abstract

Purpose of review: Many children with cancer suffer from neuropathic pain. However, there are no published pediatric randomized controlled trials (RCTs), nor agreed upon pediatric treatment recommendations. Pediatric neuropathic pain in patients with malignancies is often underassessed and undertreated with ineffective therapies.

Recent findings: This article describes main themes in the literature and commonly used treatment strategies.

Summary: A combination of integrative, rehabilitative, and supportive therapies with pharmacotherapy, including first line medications such as NSAIDs, opioids, low-dose tricyclics, and gabapentinoids, appear to be successful treatment strategies. There is a dearth of evidence regarding the management of neuropathic pain in children with cancer; studies, especially RCTs, are desperately needed.

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