Long-term risk of glaucoma after congenital cataract surgery

Abstract

Purpose: To report the long-term risk of glaucoma development in children following congenital cataract surgery.

Design: Retrospective interventional consecutive case series.

Methods: We retrospectively reviewed the records of 62 eyes of 37 children who underwent congenital cataract surgery when <7 months of age by the same surgeon using a limbal approach. The Kaplan-Meier method was used to calculate the probability of an eye's developing glaucoma and/or becoming a glaucoma suspect over time.

Results: The median age of surgery was 2.0 months and the median follow-up after cataract surgery was 7.9 years (range, 3.2-23.5 years). Nine eyes (14.5%) developed glaucoma a median of 4.3 months after cataract surgery and an additional 16 eyes (25.8%) were diagnosed as glaucoma suspects a median of 8.0 years after cataract surgery. The probability of an eye's developing glaucoma was estimated to be 19.5% (95% CI: 10.0%-36.1%) by 10 years after congenital cataract surgery. When the probability of glaucoma and glaucoma suspect were combined, the risk increased to 63.0% (95% CI: 43.6%-82.3%).

Conclusions: Long-term monitoring of eyes after congenital cataract surgery is important because we estimate that nearly two thirds of these eyes will develop glaucoma or become glaucoma suspects by 10 years after cataract surgery.

Figure

Figure Kaplan Meier curves showing cumulative probability of an eye developing glaucoma (dashed line) and glaucoma suspect or glaucoma (solid line) after congenital cataract surgery over time. The number of eyes at risk at each 5 year time interval are shown below the x axis.