Therapeutics: targeting an oncometabolite
- PMID: 23640211
- DOI: 10.1038/nrc3531
Therapeutics: targeting an oncometabolite
Comment on
-
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.Science. 2013 May 3;340(6132):626-30. doi: 10.1126/science.1236062. Epub 2013 Apr 4. Science. 2013. PMID: 23558169 Free PMC article.
-
Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation.Science. 2013 May 3;340(6132):622-6. doi: 10.1126/science.1234769. Epub 2013 Apr 4. Science. 2013. PMID: 23558173
Similar articles
-
Cancer. Silencing a metabolic oncogene.Science. 2013 May 3;340(6132):558-9. doi: 10.1126/science.1238523. Science. 2013. PMID: 23641103 Free PMC article.
-
Releasing the block: setting differentiation free with mutant IDH inhibitors.Cancer Cell. 2013 May 13;23(5):570-2. doi: 10.1016/j.ccr.2013.04.024. Cancer Cell. 2013. PMID: 23680144 Free PMC article.
-
Cancer metabolism in breadth and depth.Nat Biotechnol. 2013 Jun;31(6):505-7. doi: 10.1038/nbt.2611. Nat Biotechnol. 2013. PMID: 23752435 No abstract available.
-
IDH mutations in glioma and acute myeloid leukemia.Trends Mol Med. 2010 Sep;16(9):387-97. doi: 10.1016/j.molmed.2010.07.002. Epub 2010 Aug 5. Trends Mol Med. 2010. PMID: 20692206 Review.
-
Inhibitors of Mutant Isocitrate Dehydrogenases 1 and 2 (mIDH1/2): An Update and Perspective.J Med Chem. 2018 Oct 25;61(20):8981-9003. doi: 10.1021/acs.jmedchem.8b00159. Epub 2018 Jun 18. J Med Chem. 2018. PMID: 29847930 Review.
Cited by
-
Activation of AhR with nuclear IKKα regulates cancer stem-like properties in the occurrence of radioresistance.Cell Death Dis. 2018 May 1;9(5):490. doi: 10.1038/s41419-018-0542-9. Cell Death Dis. 2018. PMID: 29706625 Free PMC article.
-
Modeling cancer metabolism on a genome scale.Mol Syst Biol. 2015 Jun 30;11(6):817. doi: 10.15252/msb.20145307. Mol Syst Biol. 2015. PMID: 26130389 Free PMC article. Review.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical