Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Feb;5(2):124-8.
doi: 10.4103/1947-2714.107532.

Morphological spectrum of pilar cysts

Affiliations

Morphological spectrum of pilar cysts

Anikode Subramanian Ramaswamy et al. N Am J Med Sci. 2013 Feb.

Abstract

Background: Cysts of the skin are one of the commonly excised specimens in the surgical outpatient department. A majority of them being clinically diagnosed as sebaceous cysts, their true nature is only discernible on histopathological examination. Closer examination of the type of keratinization involved will throw light into the exact nature of the cyst. Trichilemmal or Pilar cyst is one such entity, which presents in both a non-neoplastic and neoplastic form.

Aims: The present retrospective observational study was undertaken to find out the incidence of these cysts in surgical pathology practice in a rural hospital and to enlist the various morphological forms that these cysts may take.

Materials and methods: The histopathology files were reviewed for a period of 6 years for cases coded as pilar cyst.

Results: A total of eight cases (5.75%) were identified, which showed features of trichilemmal differentiation. A single case each of proliferating trichilemmal cyst and malignant proliferating trichilemmal tumors were noted. Most of the cases were seen among females on the scalp.

Conclusions: Trichilemmal tumor is an uncommon histopathological entity. Many of these lesions may be mistakenly diagnosed due to lack of recognition of the unique type of keratinization.

Keywords: Malignant pilar tumor; Pilarcyst; Proliferating pilar tumor; Proliferating trichilemmal cyst.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
(a) Trichilemmal cyst showing abrupt trichilemmal type of keratinisation.(b) Epidermal cyst with granular layer. H and E, ×10
Figure 2
Figure 2
(a) Skin covered large multiloculated cyst filled with viscous material with intervening grey white nodular areas. (b) Lobules of squamous epithelium showing trichilemmal keratinisation. H and E, ×10
Figure 3
Figure 3
Exophytic skin covered growth with central ulceration
Figure 4
Figure 4
(a) Lobules of proliferating squamous epithelium with abrupt trichilemmal keratinisation and dystrophic calcification of keratin. H and E, ×10. (b) Moderate to severe nuclear atypia in the squamous epithelial cells lining the cyst. H and E, ×40

Similar articles

Cited by

References

    1. Chandrasekaran V, Parkash S, Raghuveer CV. Epidermal cysts: A- clinicopathological and biochemical study. Postgrad Med J. 1980;56:823–7. - PMC - PubMed
    1. Warvi WN, Gates O. Epithelial cysts and cystic tumors of the skin. Am J Pathol. 1943;19:765–83. - PMC - PubMed
    1. Kirkham N. Tumors and cysts of the epidermis. In: Elder DE, Elenitsas R, Johnson BL, Murphy GF, editors. Lever's Histopathology of the skin. 9th ed. Philadelphia: Lippincott Williams and Wilkins; 2005. pp. 814–6.
    1. Rosai J. Rosai and Ackerman's surgical pathology. 9th ed. Vol. 1. St Louis: Mosby; 2004. pp. 151–3.
    1. Weedon D. Skin pathology. 2nd ed. Edinburgh: Churchill Livingstone; 2002. pp. 504–7.