Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Sep:93:199-202.
doi: 10.1016/j.phytochem.2013.03.018. Epub 2013 May 1.

Cryptosporioptide: a bioactive polyketide produced by an endophytic fungus Cryptosporiopsis sp

Muhammad Saleem  1 , Muhammad Imran Tousif, Naheed Riaz, Ishtiaq Ahmed, Barbara Schulz, Muhammad Ashraf, Rumana Nasar, Gennaro Pescitelli, Hidayat Hussain, Abdul Jabbar, Nusrat Shafiq, Karsten Krohn
Affiliations

Cryptosporioptide: a bioactive polyketide produced by an endophytic fungus Cryptosporiopsis sp

Muhammad Saleem et al. Phytochemistry. 2013 Sep.

Abstract

An antibiotic polyketide, Cryptosporioptide (1) was isolated from the culture extract of the endophytic fungus Cryptosporiopsis sp. The structure of Cryptosporioptide has been established with the help of 1D ((1)H, (13)C), 2D NMR (HSQC, HMBC, COSY, NOESY) techniques and mass spectrometry (FABMS, HRFABMS). The absolute configuration was established by means of electronic circular dichroism (ECD). Cryptosporioptide exhibited both lipoxygenase inhibitory and anti-Bacillus megaterium activities.

Keywords: Anti-Bacillus megaterium; Cryptosporiopsis sp.; Endophytic fungus; Lipoxygenase inhibition; Novel polyketide; TDDFT CD calculations.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources