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Review
. 2013 May;31(2):533-55.
doi: 10.1016/j.ncl.2013.01.001. Epub 2013 Feb 16.

Multifocal motor neuropathy, multifocal acquired demyelinating sensory and motor neuropathy, and other chronic acquired demyelinating polyneuropathy variants

Mazen M Dimachkie  1 , Richard J Barohn, Jonathan Katz
Affiliations
Review

Multifocal motor neuropathy, multifocal acquired demyelinating sensory and motor neuropathy, and other chronic acquired demyelinating polyneuropathy variants

Mazen M Dimachkie et al. Neurol Clin. 2013 May.

Abstract

Chronic acquired demyelinating neuropathies (CADP) constitute an important group of immune neuromuscular disorders affecting myelin. This article discusses CADP with emphasis on multifocal motor neuropathy, multifocal acquired demyelinating sensory and motor neuropathy, distal acquired demyelinating symmetric neuropathy, and less common variants. Although each of these entities has distinctive laboratory and electrodiagnostic features that aid in their diagnosis, clinical characteristics are of paramount importance in diagnosing specific conditions and determining the most appropriate therapies. Knowledge regarding pathogenesis, diagnosis, and management of these disorders continues to expand, resulting in improved opportunities for identification and treatment.

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References

    1. Eichhorst H. Beitrage zur pathologie der nerven und muskeln. Cor Kl Schweiz Aertze. 1890;20:59–71.
    1. Austin JH. Recurrent polyneuropathies and their corticosteroids treatment. Brain. 1958;8:157–92. - PubMed
    1. Dyck PJ, Lais AC, Otha M, Bastron JA, Okasaki H, Groover RV. Chronic inflammatory polyradiculoneuropathy. Mayo Clin Proc. 1975;50:621–37. - PubMed
    1. Dyck PJ, Arnason BG. Chronic inflammatory demyelinating polyradiculoneuropathy. In: Dyck PJ, Thomas PK, Lambert EH, Bunge R, editors. Peripheral neuropathy. 2nd. Philadelphia: WB Saunders; 1984. pp. 2101–14.
    1. Dyck PJ, Oviatt KF, Lambert EH. Intensive evaluation of referred unclassified neuropathies yields improved diagnosis. Ann Neurol. 1981 Sep;10(3):222–6. - PubMed

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